NXPH4

Across TCGA cell cohorts, NXPH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,926 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NXPH4-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Regulation of stem cell population maintenance, and ATP synthesis coupled electron transport. Each is linked with NXPH4 in more than 8 cancer types. Because this analysis shows association rather than direction, both NXPH4-to-partner and partner-to-NXPH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by NXPH4-low versus NXPH4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPH4→partner) and Y-score (partner→NXPH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of stem cell population maintenance →	+0.058	+1.914	.005	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of stem cell population maintenance →	+0.079	+2.441	.009	.001	3	9
BONE	ATP synthesis coupled electron transport →	+0.113	+2.740	<.001	<.001	3	9
BONE	Mitochondrial ATP synthesis coupled electron transport →	+0.113	+2.740	<.001	<.001	3	9
SOFT_TISSUE	Alternative mRNA splicing, via spliceosome →	+0.063	+1.310	.002	.001	3	9
OESOPHAGUS	Mitochondrion organization →	+0.078	+2.132	<.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,926 associations by consensus.

Positive regulation of stem cell population maintenance by NXPH4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →