NXPH3

Across TCGA patient cohorts, NXPH3 mutation is significantly associated with the RNA expression of many other genes, with 381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NXPH3-associated genes across cancer lineages are MTCYBP10, LINC02854, and RN7SL211P. Each is linked with NXPH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NXPH3-to-partner and partner-to-NXPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCYBP10 grouped by NXPH3-low versus NXPH3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPH3→partner) and Y-score (partner→NXPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTCYBP10 →	+0.033	+4.354	.001	<.001	3	2
UCEC	LINC02854 →	+0.057	+3.466	<.001	.003	3	2
UCEC	RN7SL211P →	+0.080	+3.008	.007	.007	3	2
SKCM	OR5M13P →	+0.026	+4.797	.006	.003	3	2
UCEC	LINC01730 →	+0.396	+3.209	.001	.009	3	1
UCEC	IGKV1D-13 →	+1.507	+2.807	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

MTCYBP10 by NXPH3 expression — UCEC

Explore this box plot interactively →