NXPH1

Across TCGA cell cohorts, NXPH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 479 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NXPH1-associated GO terms across cancer lineages are Organelle fusion, Respiratory burst involved in defense response, and Vesicle localization. Each is linked with NXPH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NXPH1-to-partner and partner-to-NXPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle fusion grouped by NXPH1-low versus NXPH1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPH1→partner) and Y-score (partner→NXPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Organelle fusion →	+0.034	+0.032	<.001	.002	3	5
BREAST	Respiratory burst involved in defense response →	+0.232	+0.986	<.001	.005	3	4
BREAST	Vesicle localization →	+0.045	+1.560	.004	.002	3	3
LUNG_NSCLC_LUAD	Negative regulation of syncytium formation by plasma membrane fusion →	+0.040	+0.225	.004	.005	3	3
LUNG_NSCLC_LUAD	Ventricular cardiac muscle cell differentiation →	-0.170	-0.235	<.001	.003	3	3
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.032	+0.044	.006	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 479 associations by consensus.

Organelle fusion by NXPH1 expression — BLOOD_Lymphoma

Explore this box plot interactively →