Across TCGA cell cohorts, NXPE2 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NXPE2-associated genes across cancer lineages are PTH, SLC35G3, and OR4F6. Each is linked with NXPE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NXPE2-to-partner and partner-to-NXPE2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPE2→partner) and Y-score (partner→NXPE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PTH →	+0.027	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	SLC35G3 →	+0.007	+3.362	<.001	.007	3	1
BLOOD_Lymphoma	OR4F6 →	+0.019	+5.209	<.001	.005	3	1
LARGE_INTESTINE	RNMT →	+0.605	+2.537	.002	.008	3	1
LARGE_INTESTINE	C19orf44 →	+0.469	+3.237	.001	.003	3	1
LARGE_INTESTINE	MAPK8 →	+0.647	+2.537	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

NXPE2 survival (RNA) · tumor vs normal (RNA) · all NXPE2 data types