NXNL2

Across TCGA cell cohorts, NXNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,886 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible NXNL2-associated GO terms across cancer lineages are Positive regulation of cell-substrate adhesion, Positive regulation of plasma membrane repair, and Response to water. Each is linked with NXNL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both NXNL2-to-partner and partner-to-NXNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate adhesion grouped by NXNL2-low versus NXNL2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXNL2→partner) and Y-score (partner→NXNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate adhesion →	+0.117	+1.406	<.001	<.001	3	13
BONE	Positive regulation of plasma membrane repair →	+0.282	+0.881	<.001	.003	3	13
STOMACH	Response to water →	+0.236	+1.316	<.001	<.001	3	12
BONE	Maintenance of protein localization in organelle →	+0.121	+1.061	.004	.004	2	12
UPPER_AERODIGESTIVE_TRACT	Maintenance of protein location in cell →	+0.114	+0.930	<.001	<.001	3	11
BONE	Positive regulation of canonical NF-kappaB signal transduction →	+0.065	+1.033	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,886 associations by consensus.

Positive regulation of cell-substrate adhesion by NXNL2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →