NXNL1

Across TCGA cell cohorts, NXNL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 183 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NXNL1-associated GO terms across cancer lineages are Regulation of macrophage cytokine production, Regulation of neural precursor cell proliferation, and Detection of muscle stretch. Each is linked with NXNL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NXNL1-to-partner and partner-to-NXNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macrophage cytokine production grouped by NXNL1-low versus NXNL1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXNL1→partner) and Y-score (partner→NXNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of macrophage cytokine production →	-0.123	-0.108	<.001	.001	3	3
SKIN	Regulation of neural precursor cell proliferation →	-0.048	-0.105	.004	.009	3	2
SKIN	Detection of muscle stretch →	-0.178	-0.194	<.001	.004	3	2
SKIN	Positive regulation of phosphorylation →	-0.031	-0.154	<.001	.002	3	2
SKIN	Positive regulation of protein kinase activity →	-0.037	-0.084	.001	.003	3	2
SKIN	Carbohydrate phosphorylation →	+0.054	+0.147	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

Regulation of macrophage cytokine production by NXNL1 expression — SKIN

Explore this box plot interactively →