Across TCGA patient cohorts, NXF4 mutation is significantly associated with the RNA expression of many other genes, with 5,783 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NXF4-associated genes across cancer lineages are PIGW, NF1P6, and CIP2A. Each is linked with NXF4 in more than 2 cancer types. Because this analysis shows association rather than direction, both NXF4-to-partner and partner-to-NXF4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF4→partner) and Y-score (partner→NXF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIGW →	+0.697	+2.818	<.001	<.001	3	3
CESC	NF1P6 →	+0.248	+5.342	<.001	.002	3	3
UCEC	CIP2A →	+0.615	+1.784	<.001	<.001	3	3
UCEC	C18orf54 →	+0.590	+2.099	<.001	<.001	3	3
UCEC	BNIP3 →	+0.781	+2.000	<.001	<.001	3	3
UCEC	FAM210A →	+0.441	+3.130	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,783 associations by consensus.

Exploration

NXF4 survival (RNA) · tumor vs normal (RNA) · all NXF4 data types