NXF3

Across TCGA cell cohorts, NXF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,914 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NXF3-associated GO terms across cancer lineages are Response to oxygen levels, Positive regulation of protein transport, and Regulation of protein localization to membrane. Each is linked with NXF3 in more than 6 cancer types. Because this analysis shows association rather than direction, both NXF3-to-partner and partner-to-NXF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to oxygen levels grouped by NXF3-low versus NXF3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF3→partner) and Y-score (partner→NXF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Response to oxygen levels →	+0.036	+0.200	.004	.007	3	7
SOFT_TISSUE	Positive regulation of protein transport →	+0.032	+0.321	.009	.003	3	6
PANCREAS	Regulation of protein localization to membrane →	+0.071	+0.692	<.001	.006	2	7
SOFT_TISSUE	Multi-pass transmembrane protein insertion into ER membrane →	+0.098	+0.369	.001	.003	3	6
BLOOD_Lymphoma	Positive regulation of viral life cycle →	+0.086	+0.383	<.001	<.001	3	5
BREAST	Regulation of muscle cell apoptotic process →	+0.053	+0.172	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

Response to oxygen levels by NXF3 expression — OVARY

Explore this box plot interactively →