NXF2

Across TCGA patient cohorts, NXF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,333 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NXF2-associated GO terms across cancer lineages are Spindle assembly, Telomere organization, and Mitochondrial translation. Each is linked with NXF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NXF2-to-partner and partner-to-NXF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by NXF2-low versus NXF2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF2→partner) and Y-score (partner→NXF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spindle assembly →	+0.051	+0.024	<.001	.001	3	9
STAD	Telomere organization →	+0.048	+0.027	<.001	<.001	3	9
ESCA	Mitochondrial translation →	+0.068	+0.043	<.001	.003	2	10
ESCA	Mitochondrial gene expression →	+0.061	+0.039	<.001	.005	2	10
ESCA	rRNA transcription →	+0.057	+0.037	<.001	.001	3	9
STAD	Cytokinesis →	+0.049	+0.041	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,333 associations by consensus.

Spindle assembly by NXF2 expression — STAD

Explore this box plot interactively →