NVL

Across TCGA patient cohorts, NVL protein abundance is significantly associated with the RNA expression of many other genes, with 7,578 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NVL-associated genes across cancer lineages are DTL, URB2, and UBE2T. Each is linked with NVL in more than 7 cancer types. Because this analysis shows association rather than direction, both NVL-to-partner and partner-to-NVL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NVL versus DTL in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NVL→partner) and Y-score (partner→NVL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DTL →	+0.974	+0.325	<.001	<.001	3	8
UCEC	URB2 →	+0.789	+0.362	<.001	<.001	3	7
UCEC	UBE2T →	+1.201	+0.328	<.001	<.001	3	7
UCEC	GAS5 →	+0.624	+0.236	<.001	.001	3	6
GBM	TIMELESS →	+0.787	+0.391	<.001	<.001	3	6
BRCA	NEK2 →	+1.063	+0.357	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,578 associations by consensus.

NVL vs DTL — BRCA

Explore this scatter interactively →