NVL

Across TCGA patient cohorts, NVL protein abundance is significantly associated with the protein abundance of many other proteins, with 16,017 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NVL-associated proteins across cancer lineages are C1orf35, HNRNPK, and IPO9. Each is linked with NVL in more than 7 cancer types. Because this analysis shows association rather than direction, both NVL-to-partner and partner-to-NVL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NVL versus C1orf35 in OV, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NVL→partner) and Y-score (partner→NVL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C1orf35 →	+0.552	+0.352	.001	<.001	3	8
GBM	HNRNPK →	+0.190	+0.244	<.001	<.001	3	7
BRCA	IPO9 →	+0.338	+0.233	<.001	<.001	3	7
GBM	FEN1 →	+0.602	+0.436	<.001	<.001	3	7
OV	RRP15 →	+0.602	+0.352	<.001	<.001	2	8
OV	PARP1 →	+0.428	+0.284	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,017 associations by consensus.

NVL vs C1orf35 — OV

Explore this scatter interactively →