NUTF2

Across TCGA patient cohorts, NUTF2 mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUTF2-associated genes across cancer lineages are SNORD90, MIR7159, and LGALS13. Each is linked with NUTF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUTF2-to-partner and partner-to-NUTF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD90 grouped by NUTF2-low versus NUTF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUTF2→partner) and Y-score (partner→NUTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD90 →	+0.396	+3.032	<.001	<.001	3	2
BRCA	MIR7159 →	+0.523	+5.317	<.001	.006	3	1
SKCM	LGALS13 →	+0.067	+5.292	<.001	.006	3	1
UCEC	MRPL39 →	+0.523	+3.595	.003	.001	3	1
UCEC	C16orf87 →	+0.606	+3.332	.002	.005	3	1
UCEC	WHAMM →	+0.431	+3.201	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

SNORD90 by NUTF2 expression — UCEC

Explore this box plot interactively →