NUTF2

Across TCGA cell cohorts, NUTF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,208 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUTF2-associated GO terms across cancer lineages are Regulation of establishment of protein localization to telomere, Double-strand break repair via break-induced replication, and Regulation of centromeric sister chromatid cohesion. Each is linked with NUTF2 in more than 15 cancer types. Because this analysis shows association rather than direction, both NUTF2-to-partner and partner-to-NUTF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of establishment of protein localization to telomere grouped by NUTF2-low versus NUTF2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUTF2→partner) and Y-score (partner→NUTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of establishment of protein localization to telomere →	+0.127	+0.632	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.230	+0.643	.002	.003	3	16
BREAST	Regulation of centromeric sister chromatid cohesion →	+0.136	+0.795	.003	<.001	3	15
LIVER	Regulation of DNA replication →	+0.067	+0.798	.004	<.001	3	14
PANCREAS	Cell cycle DNA replication initiation →	+0.161	+0.534	<.001	.001	3	13
PANCREAS	Nuclear cell cycle DNA replication initiation →	+0.161	+0.534	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,208 associations by consensus.

Regulation of establishment of protein localization to telomere by NUTF2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →