NUSAP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NUSAP1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NUSAP1 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NUSAP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUSAP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

HNSC and LSCC are the cancer types where NUSAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileII,III,IV0.8581.000.0322view →
LSCCOSMedianAll1.0000.633.0252view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NUSAP1–HNSC (OS)

Kaplan–Meier survival curve for NUSAP1 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration