Across TCGA pan-cancer cohorts, NUSAP1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NUSAP1 data layer compared with 28 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NUSAP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUSAP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.
HNSC and LSCC are the cancer types where NUSAP1 mass-spec protein most reproducibly stratifies survival.