NUS1P2

Across TCGA pan-cancer cohorts, NUS1P2 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NUS1P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NUS1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types NUS1P2 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, LUAD, and KIRP are the cancer types where NUS1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUS1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−3.001	<.001	11	view →
LUAD	Male	II,III,IV	+1.194	<.001	11	view →
KIRP	Male	All	+1.687	<.001	8	view →
COAD	Female	All	−0.967	<.001	7	view →
UCEC	All	III,IV	+2.085	.004	6	view →
KIRC	Male	All	+1.049	<.001	6	view →
LUSC	All	All	+0.816	<.001	4	view →
BRCA	Female	II,III,IV	+0.435	<.001	4	view →
CHOL	All	II,III,IV	+2.700	.003	2	view →
READ	All	All	−0.785	<.001	2	view →
PRAD	All	All	−0.191	.018	2	view →
STAD	Female	All	−0.172	.048	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NUS1P2–KICH

Open the KICH breakdown →