NUS1

Across TCGA cell cohorts, NUS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,463 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NUS1-associated GO terms across cancer lineages are Spermidine biosynthetic process, 7-methylguanosine mRNA capping, and Spermine biosynthetic process. Each is linked with NUS1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NUS1-to-partner and partner-to-NUS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermidine biosynthetic process grouped by NUS1-low versus NUS1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUS1→partner) and Y-score (partner→NUS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Spermidine biosynthetic process →	+0.155	+0.475	<.001	<.001	3	17
SKIN	7-methylguanosine mRNA capping →	+0.111	+0.785	<.001	<.001	3	16
BREAST	Spermine biosynthetic process →	+0.192	+0.795	<.001	<.001	3	16
SKIN	7-methylguanosine RNA capping →	+0.111	+0.785	<.001	<.001	3	16
KIDNEY	Protein localization to condensed chromosome →	+0.163	+0.756	.001	.002	3	15
OVARY	DNA alkylation repair →	+0.123	+0.846	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,463 associations by consensus.

Spermidine biosynthetic process by NUS1 expression — BREAST

Explore this box plot interactively →