Across TCGA cell cohorts, NUPR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 268 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUPR2-associated GO terms across cancer lineages are Positive regulation of microtubule depolymerization, Cell adhesion mediated by integrin, and Positive regulation of neuron differentiation. Each is linked with NUPR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUPR2-to-partner and partner-to-NUPR2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUPR2→partner) and Y-score (partner→NUPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of microtubule depolymerization →	-0.095	-0.338	<.001	.003	3	4
BLOOD_Lymphoma	Cell adhesion mediated by integrin →	-0.105	-0.025	.002	.002	3	3
BLOOD_Lymphoma	Positive regulation of neuron differentiation →	-0.060	-0.025	.003	.002	3	3
BLOOD_Lymphoma	Negative regulation of actin nucleation →	+0.107	+0.021	.004	.009	3	3
LUNG_SCLC	Positive regulation of sister chromatid cohesion →	+0.057	+0.776	.003	.004	3	3
LUNG_NSCLC_LUAD	Establishment of endothelial intestinal barrier →	+0.112	+0.554	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 268 associations by consensus.

Exploration

NUPR2 survival (RNA) · tumor vs normal (RNA) · all NUPR2 data types