NUP93

Across TCGA patient cohorts, NUP93 mutation is significantly associated with the RNA expression of many other genes, with 1,866 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP93-associated genes across cancer lineages are OR7E97P, RNU6-1252P, and SLC25A4. Each is linked with NUP93 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUP93-to-partner and partner-to-NUP93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E97P grouped by NUP93-low versus NUP93-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP93→partner) and Y-score (partner→NUP93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	OR7E97P →	+0.393	+5.578	<.001	.002	3	4
ESCA	RNU6-1252P →	+0.294	+5.681	<.001	.003	3	3
UCEC	SLC25A4 →	+0.382	+1.711	.004	.001	3	3
LUSC	FAM96AP1 →	+0.341	+5.578	<.001	.002	3	3
HNSC	RPL26P31 →	+0.137	+3.597	<.001	.007	3	3
UCEC	CDCA2 →	+0.594	+1.668	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,866 associations by consensus.

OR7E97P by NUP93 expression — LUSC

Explore this box plot interactively →