NUP93

Across TCGA cell cohorts, NUP93 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,872 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUP93-associated GO terms across cancer lineages are Mitotic chromosome movement towards spindle pole, Regulation of nuclear division, and Double-strand break repair via break-induced replication. Each is linked with NUP93 in more than 18 cancer types. Because this analysis shows association rather than direction, both NUP93-to-partner and partner-to-NUP93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome movement towards spindle pole grouped by NUP93-low versus NUP93-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP93→partner) and Y-score (partner→NUP93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Mitotic chromosome movement towards spindle pole →	+0.158	+1.116	<.001	<.001	3	19
SOFT_TISSUE	Regulation of nuclear division →	+0.129	+1.003	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.255	+1.018	<.001	<.001	3	18
BLOOD_Myeloma	Mitotic DNA replication →	+0.198	+1.295	<.001	<.001	3	18
BLOOD_Myeloma	Cell cycle DNA replication →	+0.158	+1.386	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Positive regulation of mitotic cell cycle phase transition →	+0.111	+1.007	.001	.006	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

Mitotic chromosome movement towards spindle pole by NUP93 expression — KIDNEY

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