NUP93

Across TCGA cell cohorts, NUP93 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NUP93-associated genes across cancer lineages are KRTAP10-6, ACTBL2, and KLK15. Each is linked with NUP93 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP93-to-partner and partner-to-NUP93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-6 grouped by NUP93-low versus NUP93-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP93→partner) and Y-score (partner→NUP93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KRTAP10-6 →	+0.038	+3.347	<.001	.005	3	2
BLOOD_Leukemia	ACTBL2 →	+0.020	+3.502	<.001	.005	3	1
BLOOD_Leukemia	KLK15 →	+0.398	+3.354	<.001	.001	3	1
BLOOD_Leukemia	OR10K2 →	+0.032	+3.121	<.001	.003	3	1
BLOOD_Leukemia	OR10R2 →	+1.180	+2.966	<.001	.005	3	1
BLOOD_Leukemia	TCEAL6 →	+0.027	+3.718	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

KRTAP10-6 by NUP93 expression — LARGE_INTESTINE

Explore this box plot interactively →