NUP88

Across TCGA patient cohorts, NUP88 protein abundance is significantly associated with the RNA expression of many other genes, with 18,431 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP88-associated genes across cancer lineages are FOXM1, PTPRB, and PLPP1. Each is linked with NUP88 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUP88-to-partner and partner-to-NUP88 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP88 versus FOXM1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP88→partner) and Y-score (partner→NUP88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FOXM1 →	+1.429	+0.155	<.001	.001	3	6
BRCA	PTPRB →	-0.867	-0.179	<.001	<.001	3	6
OV	PLPP1 →	-0.742	-0.177	<.001	.001	3	6
OV	IRAG1 →	-1.115	-0.188	.001	.001	3	6
HNSC	MBTD1 →	+0.639	+0.145	.001	<.001	3	6
HNSC	GTF3C2 →	+0.462	+0.111	.006	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,431 associations by consensus.

NUP88 vs FOXM1 — BRCA

Explore this scatter interactively →