NUP88

Across TCGA cell cohorts, NUP88 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,974 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUP88-associated GO terms across cancer lineages are Telomere assembly, Ribosomal small subunit export from nucleus, and 'de novo' IMP biosynthetic process. Each is linked with NUP88 in more than 16 cancer types. Because this analysis shows association rather than direction, both NUP88-to-partner and partner-to-NUP88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by NUP88-low versus NUP88-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP88→partner) and Y-score (partner→NUP88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.135	+0.567	<.001	<.001	3	17
URINARY_TRACT	Ribosomal small subunit export from nucleus →	+0.131	+1.002	.005	.002	3	16
LIVER	'de novo' IMP biosynthetic process →	+0.149	+0.836	.005	<.001	3	15
LUNG_SCLC	Cajal body organization →	+0.157	+0.567	<.001	.007	3	14
URINARY_TRACT	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.106	+0.922	.007	.005	2	15
SOFT_TISSUE	DNA-templated DNA replication →	+0.121	+0.847	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,974 associations by consensus.

Telomere assembly by NUP88 expression — LUNG_SCLC

Explore this box plot interactively →