NUP85

Across TCGA cell cohorts, NUP85 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,921 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUP85-associated GO terms across cancer lineages are Nuclear DNA replication, Cell cycle DNA replication, and DNA replication checkpoint signaling. Each is linked with NUP85 in more than 19 cancer types. Because this analysis shows association rather than direction, both NUP85-to-partner and partner-to-NUP85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear DNA replication grouped by NUP85-low versus NUP85-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP85→partner) and Y-score (partner→NUP85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear DNA replication →	+0.211	+0.918	<.001	<.001	3	20
BONE	Cell cycle DNA replication →	+0.209	+0.868	<.001	.001	3	20
BONE	DNA replication checkpoint signaling →	+0.256	+0.922	<.001	.003	3	19
BONE	Positive regulation of nuclear cell cycle DNA replication →	+0.150	+1.009	.006	.001	3	18
BONE	Mitotic DNA replication →	+0.248	+0.960	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle process →	+0.074	+0.850	.003	<.001	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,921 associations by consensus.

Nuclear DNA replication by NUP85 expression — BONE

Explore this box plot interactively →