NUP62CL

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NUP62CL Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NUP62CL data layer compared with 23 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NUP62CL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NUP62CL expression acts as an unfavorable survival marker.

HNSC and LUAD are the cancer types where NUP62CL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.0810.768<.00148view →
LUADOSMedianAll0.2230.835<.00130view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration