Across TCGA pan-cancer cohorts, NUP62 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUP62 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NUP62 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NUP62 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where NUP62 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.902	0.492	.002	53	view →
CCRCC	OS	Median	All	0.818	0.968	.009	11	view →
HNSC	DFS	Median	III,IV	0.291	1.000	.001	11	view →
PDAC	OS	Median	IV	0.951	0.381	.006	6	view →
LSCC	DFS	Median	II,III,IV	0.834	0.569	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: NUP62 tumor-vs-normal RNA expression · all NUP62 data types