Across TCGA patient cohorts, NUP62 protein abundance is significantly associated with the RNA expression of many other genes, with 15,850 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP62-associated genes across cancer lineages are S1PR1, AOC3, and HSPB8. Each is linked with NUP62 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUP62-to-partner and partner-to-NUP62 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP62→partner) and Y-score (partner→NUP62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	S1PR1 →	-0.828	-0.174	<.001	.002	3	6
BRCA	AOC3 →	-1.316	-0.207	<.001	<.001	3	5
GBM	HSPB8 →	-1.343	-0.223	<.001	<.001	3	5
COAD	LMOD1 →	-1.051	-0.100	.001	.003	3	5
OV	HOPX →	-1.097	-0.199	.001	<.001	3	5
GBM	DACT3 →	-0.745	-0.227	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,850 associations by consensus.

Exploration

NUP62 survival (RNA) · tumor vs normal (RNA) · all NUP62 data types