Across TCGA patient cohorts, NUP62 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP62-associated genes across cancer lineages are GAPDH, MEK1, and p27_pT198. Each is linked with NUP62 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP62-to-partner and partner-to-NUP62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP62→partner) and Y-score (partner→NUP62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.414	+1.874	.040	.049	3	2
UCEC	MEK1 →	+0.354	+3.807	.009	<.001	3	2
UCEC	p27_pT198 →	+0.079	+1.765	.049	.014	3	2
UCEC	ATM →	-0.603	-3.700	<.001	.001	3	2
UCEC	eEF2 →	+0.305	+1.874	.023	.049	3	1
UCEC	eIF4E →	+0.175	+3.472	.027	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

NUP62 survival (RNA) · tumor vs normal (RNA) · all NUP62 data types