Across TCGA cell cohorts, NUP62 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible NUP62-associated genes across cancer lineages are OR1N2, BARHL2, and NTSR2. Each is linked with NUP62 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP62-to-partner and partner-to-NUP62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP62→partner) and Y-score (partner→NUP62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR1N2 →	+0.039	+4.705	<.001	.003	3	2
OESOPHAGUS	BARHL2 →	+0.047	+4.017	.005	.007	3	1
OESOPHAGUS	NTSR2 →	+0.036	+4.392	.004	.003	3	1
OESOPHAGUS	VWC2L →	+0.012	+4.392	<.001	.003	3	1
OESOPHAGUS	TPRX1 →	+0.019	+4.392	<.001	.003	3	1
OESOPHAGUS	PLA2G2C →	+0.039	+4.017	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

NUP62 survival (RNA) · tumor vs normal (RNA) · all NUP62 data types