NUP50P1

Across TCGA pan-cancer cohorts, NUP50P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of NUP50P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NUP50P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUP50P1 is over-expressed in tumor, although a few such as PAAD and KICH show the opposite, repressed pattern.

HNSC, LUAD, and PAAD are the cancer types where NUP50P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUP50P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.041	.006	6	view →
LUAD	All	All	+0.060	<.001	5	view →
PAAD	All	All	−0.067	.024	4	view →
LUSC	Male	All	+0.040	<.001	4	view →
KICH	All	All	−0.055	.027	2	view →
THCA	All	IV	−0.067	.038	1	view →
BLCA	All	III,IV	+0.033	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

NUP50P1–HNSC

Open the HNSC breakdown →