NUP50

Across TCGA patient cohorts, NUP50 protein abundance is significantly associated with the RNA expression of many other genes, with 12,583 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUP50-associated genes across cancer lineages are GTSE1, MCM5, and PBK. Each is linked with NUP50 in more than 9 cancer types. Because this analysis shows association rather than direction, both NUP50-to-partner and partner-to-NUP50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP50 versus GTSE1 in GBM, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP50→partner) and Y-score (partner→NUP50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTSE1 →	+1.014	+0.322	<.001	<.001	3	9
UCEC	MCM5 →	+0.909	+0.211	.003	.002	1	10
GBM	PBK →	+1.441	+0.391	<.001	<.001	3	8
UCEC	CDCA2 →	+1.263	+0.267	<.001	<.001	3	8
UCEC	CDC6 →	+1.030	+0.295	<.001	<.001	3	8
UCEC	CENPM →	+1.235	+0.177	.001	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,583 associations by consensus.

NUP50 vs GTSE1 — GBM

Explore this scatter interactively →