NUP42

Across TCGA cell cohorts, NUP42 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NUP42-associated genes across cancer lineages are RBMY1F, OR10J3, and HBG1. Each is linked with NUP42 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP42-to-partner and partner-to-NUP42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1F grouped by NUP42-low versus NUP42-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP42→partner) and Y-score (partner→NUP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RBMY1F →	+0.204	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR10J3 →	+0.018	+5.228	<.001	.005	3	1
LARGE_INTESTINE	HBG1 →	+0.104	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RBMY1F by NUP42 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →