NUP37

Across TCGA pan-cancer cohorts, NUP37 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NUP37 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NUP37 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUP37 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, LSCC, and COAD are the cancer types where NUP37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.660	0.935	<.001	76	view →
LSCC	DFS	Tertile	II,III,IV	0.948	0.470	<.001	37	view →
COAD	DFS	Quartile	II,III,IV	0.805	1.000	.029	36	view →
UCEC	OS	Quartile	All	0.873	1.000	.023	28	view →
HNSC	OS	Quartile	All	0.155	0.793	.045	12	view →
LUAD	OS	Tertile	All	0.916	0.760	.027	9	view →
PDAC	OS	Tertile	II,III,IV	0.311	0.521	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NUP37–CCRCC (OS)

Open the CCRCC breakdown →