Across TCGA pan-cancer cohorts, NUP35P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NUP35P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NUP35P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUP35P1 is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

COAD, LUSC, and KIRC are the cancer types where NUP35P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUP35P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.076	<.001	7	view →
LUSC	Female	All	−0.088	<.001	6	view →
KIRC	All	All	+0.031	.006	3	view →
BRCA	All	III,IV	−0.066	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NUP35P1 RNA expression & survival · all NUP35P1 data types