NUP214

Across TCGA cell cohorts, NUP214 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,611 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUP214-associated GO terms across cancer lineages are RNA export from nucleus, mRNA export from nucleus, and Establishment of RNA localization. Each is linked with NUP214 in more than 16 cancer types. Because this analysis shows association rather than direction, both NUP214-to-partner and partner-to-NUP214 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by NUP214-low versus NUP214-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP214→partner) and Y-score (partner→NUP214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	RNA export from nucleus →	+0.121	+0.912	<.001	<.001	3	17
BONE	mRNA export from nucleus →	+0.108	+0.810	<.001	<.001	3	17
BONE	Establishment of RNA localization →	+0.100	+0.865	<.001	<.001	3	17
BONE	Nucleic acid transport →	+0.099	+0.767	<.001	<.001	3	17
BONE	RNA transport →	+0.099	+0.767	<.001	<.001	3	17
LUNG_NSCLC_LUAD	CTP salvage →	+0.119	+0.527	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,611 associations by consensus.

RNA export from nucleus by NUP214 expression — PANCREAS

Explore this box plot interactively →