NUP188

Across TCGA patient cohorts, NUP188 protein abundance is significantly associated with the protein abundance of many other proteins, with 31,618 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP188-associated proteins across cancer lineages are CTR9, SF3B1, and SMARCA5. Each is linked with NUP188 in more than 9 cancer types. Because this analysis shows association rather than direction, both NUP188-to-partner and partner-to-NUP188 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP188 versus CTR9 in GBM, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP188→partner) and Y-score (partner→NUP188) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTR9 →	+0.262	+0.196	<.001	<.001	3	10
GBM	SF3B1 →	+0.309	+0.212	<.001	<.001	3	10
GBM	SMARCA5 →	+0.420	+0.219	<.001	<.001	3	10
GBM	SNRNP200 →	+0.332	+0.220	<.001	<.001	3	10
BRCA	TRRAP →	+0.268	+0.259	<.001	<.001	3	10
LSCC	USP39 →	+0.429	+0.227	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 31,618 associations by consensus.

NUP188 vs CTR9 — GBM

Explore this scatter interactively →