NUP188

Across TCGA cell cohorts, NUP188 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUP188-associated GO terms across cancer lineages are Nuclear export, RNA export from nucleus, and Nucleic acid transport. Each is linked with NUP188 in more than 19 cancer types. Because this analysis shows association rather than direction, both NUP188-to-partner and partner-to-NUP188 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by NUP188-low versus NUP188-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP188→partner) and Y-score (partner→NUP188) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nuclear export →	+0.112	+1.275	<.001	<.001	3	20
SOFT_TISSUE	RNA export from nucleus →	+0.142	+1.315	<.001	<.001	3	20
SOFT_TISSUE	Nucleic acid transport →	+0.109	+1.310	<.001	<.001	3	20
SOFT_TISSUE	RNA transport →	+0.109	+1.310	<.001	<.001	3	20
BONE	Nuclear transport →	+0.107	+1.233	<.001	<.001	3	19
BONE	DNA-templated transcription initiation →	+0.086	+1.020	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,217 associations by consensus.

Nuclear export by NUP188 expression — SOFT_TISSUE

Explore this box plot interactively →