NUP160

Across TCGA patient cohorts, NUP160 mutation is significantly associated with the RNA expression of many other genes, with 2,797 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP160-associated genes across cancer lineages are CDCA2, MYO15B, and GCAT. Each is linked with NUP160 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUP160-to-partner and partner-to-NUP160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by NUP160-low versus NUP160-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP160→partner) and Y-score (partner→NUP160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CDCA2 →	+1.042	+3.182	<.001	.009	3	4
UCEC	MYO15B →	-0.590	-1.785	.001	<.001	3	3
UCEC	GCAT →	+0.493	+2.983	.002	<.001	3	3
STAD	MCAT →	+0.590	+3.186	<.001	.009	3	3
UCEC	APOBEC3H →	+0.350	+1.627	.007	.001	3	3
UCEC	CINP →	+0.309	+2.104	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,797 associations by consensus.

CDCA2 by NUP160 expression — STAD

Explore this box plot interactively →