NUP160

Across TCGA cell cohorts, NUP160 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUP160-associated genes across cancer lineages are LIPN, SLC17A1, and UBE2U. Each is linked with NUP160 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUP160-to-partner and partner-to-NUP160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIPN grouped by NUP160-low versus NUP160-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP160→partner) and Y-score (partner→NUP160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LIPN →	+0.025	+3.362	<.001	.007	3	3
OESOPHAGUS	SLC17A1 →	+0.022	+4.392	<.001	.003	3	1
OESOPHAGUS	UBE2U →	+0.136	+4.017	.001	.007	3	1
OESOPHAGUS	OR52H1 →	+0.020	+4.392	.002	.003	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	AGRP →	+0.062	+3.825	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

LIPN by NUP160 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →