NUP155

Across TCGA pan-cancer cohorts, NUP155 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUP155 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NUP155 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUP155 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where NUP155 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.331	0.611	<.001	112	view →
CCRCC	DFS	Quartile	All	0.654	0.960	.001	64	view →
HNSC	DFS	Median	III,IV	0.903	1.000	.004	32	view →
LSCC	DFS	Tertile	II,III,IV	0.881	0.476	.008	8	view →
LUAD	DFS	Median	III,IV	0.716	0.332	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NUP155–PDAC (OS)

Open the PDAC breakdown →