NUP155

Across TCGA cell cohorts, NUP155 mutation is significantly associated with the RNA expression of many other genes, with 1,284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUP155-associated genes across cancer lineages are USP26, MTFMT, and ATE1. Each is linked with NUP155 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUP155-to-partner and partner-to-NUP155 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP26 grouped by NUP155-low versus NUP155-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP155→partner) and Y-score (partner→NUP155) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	USP26 →	+0.019	+3.857	.002	.002	3	2
LARGE_INTESTINE	MTFMT →	+0.571	+3.321	.001	.003	3	2
LARGE_INTESTINE	ATE1 →	+0.541	+2.502	.003	.005	3	2
LARGE_INTESTINE	TRIM37 →	+0.692	+3.628	<.001	<.001	3	2
LARGE_INTESTINE	GPR63 →	+0.870	+2.502	<.001	.005	3	2
LARGE_INTESTINE	CLPP →	+0.469	+2.588	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,284 associations by consensus.

USP26 by NUP155 expression — OESOPHAGUS

Explore this box plot interactively →