NUP107

Across TCGA pan-cancer cohorts, NUP107 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUP107 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NUP107 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NUP107 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where NUP107 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.633	0.935	.001	69	view →
CCRCC	OS	Tertile	All	0.733	0.964	.004	33	view →
PDAC	OS	Quartile	All	0.389	0.614	.005	19	view →
LSCC	DFS	Quartile	II,III,IV	0.929	0.363	.002	9	view →
LUAD	DFS	Tertile	III,IV	0.746	0.246	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NUP107–HNSC (DFS)

Open the HNSC breakdown →