NUP107

Across TCGA patient cohorts, NUP107 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP107-associated genes across cancer lineages are Caspase-7-cleavedD198, c-Met_pY1235, and ASNS. Each is linked with NUP107 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUP107-to-partner and partner-to-NUP107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by NUP107-low versus NUP107-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP107→partner) and Y-score (partner→NUP107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.661	+1.827	.002	.015	3	3
UCEC	c-Met_pY1235 →	+0.055	+1.495	.044	.034	3	3
SKCM	ASNS →	+0.544	+2.321	.011	.035	3	2
UCEC	FASN →	+0.294	+1.502	.042	.030	3	2
UCEC	Annexin_VII →	-0.123	-2.449	.016	.019	3	2
UCEC	Shc_pY317 →	-0.152	-1.847	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Caspase-7-cleavedD198 by NUP107 expression — UCEC

Explore this box plot interactively →