NUP107

Across TCGA cell cohorts, NUP107 mutation is significantly associated with the RNA expression of many other genes, with 305 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUP107-associated genes across cancer lineages are OR1N1, PABPN1L, and OR13C5. Each is linked with NUP107 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP107-to-partner and partner-to-NUP107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1N1 grouped by NUP107-low versus NUP107-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP107→partner) and Y-score (partner→NUP107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR1N1 →	+0.066	+3.234	<.001	.008	3	2
URINARY_TRACT	PABPN1L →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	OR13C5 →	+0.760	+5.087	<.001	.004	3	1
BLOOD_Myeloma	KCNA10 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SPATA19 →	+0.033	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CETN1 →	+0.006	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 305 associations by consensus.

OR1N1 by NUP107 expression — BLOOD_Leukemia

Explore this box plot interactively →