Across TCGA patient cohorts, NUGGC RNA expression is significantly associated with the protein abundance of many other proteins, with 15,606 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUGGC-associated proteins across cancer lineages are PTPN7, RAC2, and RASAL3. Each is linked with NUGGC in more than 9 cancer types. Because this analysis shows association rather than direction, both NUGGC-to-partner and partner-to-NUGGC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUGGC→partner) and Y-score (partner→NUGGC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PTPN7 →	+0.601	+0.769	<.001	<.001	3	10
BRCA	RAC2 →	+0.830	+0.676	<.001	<.001	3	10
LSCC	RASAL3 →	+0.589	+1.348	<.001	<.001	3	10
LSCC	DOCK8 →	+0.611	+1.374	<.001	<.001	3	10
BRCA	SEPTIN1 →	+0.973	+0.830	<.001	<.001	3	9
LSCC	SEPTIN6 →	+0.545	+1.330	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,606 associations by consensus.

Exploration

NUGGC survival (RNA) · tumor vs normal (RNA) · all NUGGC data types