NUFIP2

Across TCGA patient cohorts, NUFIP2 mutation is significantly associated with the RNA expression of many other genes, with 3,094 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUFIP2-associated genes across cancer lineages are MIR3912, TRIAP1P1, and RN7SL371P. Each is linked with NUFIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUFIP2-to-partner and partner-to-NUFIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3912 grouped by NUFIP2-low versus NUFIP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUFIP2→partner) and Y-score (partner→NUFIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3912 →	+0.402	+4.941	<.001	.002	3	2
BRCA	TRIAP1P1 →	+0.148	+5.162	<.001	.004	3	2
CESC	RN7SL371P →	+0.191	+4.304	.002	.003	3	2
UCEC	DSN1 →	+0.364	+1.975	.009	<.001	3	2
UCEC	NEIL2 →	+0.429	+1.536	.001	.002	3	2
UCEC	EME1 →	+0.465	+2.545	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,094 associations by consensus.

MIR3912 by NUFIP2 expression — BRCA

Explore this box plot interactively →