NUFIP1

Across TCGA pan-cancer cohorts, NUFIP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NUFIP1 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NUFIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NUFIP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

UCEC, CCRCC, and LSCC are the cancer types where NUFIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.775	0.967	.027	4	view →
CCRCC	OS	Median	All	0.417	1.000	.027	3	view →
LSCC	DFS	Quartile	All	0.866	0.649	.017	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NUFIP1–UCEC (DFS)

Open the UCEC breakdown →