NUF2

Across TCGA patient cohorts, NUF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 28,318 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUF2-associated proteins across cancer lineages are RFC2, RIF1, and TRIP13. Each is linked with NUF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NUF2-to-partner and partner-to-NUF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUF2 versus RFC2 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUF2→partner) and Y-score (partner→NUF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.436	+1.095	<.001	<.001	3	10
LSCC	RIF1 →	+0.559	+1.222	<.001	<.001	3	10
LUAD	TRIP13 →	+1.045	+1.331	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.350	+1.344	<.001	<.001	3	10
LUAD	RRM2 →	+1.053	+1.438	<.001	<.001	3	10
LUAD	RRP36_S73 →	+0.939	+1.296	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,318 associations by consensus.

NUF2 vs RFC2 — LSCC

Explore this scatter interactively →