NUF2

Across TCGA patient cohorts, NUF2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,934 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUF2-associated genes across cancer lineages are GINS1, TTK, and CDC20. Each is linked with NUF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NUF2-to-partner and partner-to-NUF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUF2 versus GINS1 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUF2→partner) and Y-score (partner→NUF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	+1.022	+0.659	<.001	<.001	3	8
BRCA	TTK →	+1.354	+0.577	<.001	<.001	3	8
UCEC	CDC20 →	+1.946	+0.644	<.001	<.001	3	8
BRCA	NEK2 →	+1.314	+0.594	<.001	<.001	3	8
GBM	CENPF →	+1.418	+0.837	<.001	<.001	3	8
OV	KIF14 →	+1.405	+0.786	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,934 associations by consensus.

NUF2 vs GINS1 — UCEC

Explore this scatter interactively →