NUDT9

Across TCGA pan-cancer cohorts, NUDT9 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NUDT9 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NUDT9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NUDT9 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LSCC are the cancer types where NUDT9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.909	.010	36	view →
PDAC	DFS	Median	All	0.497	0.310	.001	29	view →
LSCC	OS	Tertile	III,IV	0.470	0.891	.011	8	view →
LUAD	DFS	Quartile	III,IV	0.453	0.807	.032	8	view →
UCEC	OS	Quartile	All	1.000	0.885	.044	2	view →
HNSC	DFS	Tertile	IV	0.598	0.789	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NUDT9–COAD (DFS)

Open the COAD breakdown →