NUDT9

Across TCGA patient cohorts, NUDT9 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT9-associated genes across cancer lineages are GAPDH, Di-Ras3, and eIF4E. Each is linked with NUDT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT9-to-partner and partner-to-NUDT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by NUDT9-low versus NUDT9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT9→partner) and Y-score (partner→NUDT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.611	+3.169	.038	.020	3	1
UCEC	Di-Ras3 →	-0.230	-3.169	.004	.020	3	1
UCEC	eIF4E →	+0.232	+3.169	.045	.020	2	1
UCEC	Caspase-8 →	-0.280	-3.169	.042	.020	2	1
UCEC	4E-BP1_pT70 →	+0.189	+3.169	.002	.020	2	1
UCEC	ATM →	-0.581	-3.169	.019	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GAPDH by NUDT9 expression — UCEC

Explore this box plot interactively →